Oral Kaposi's sarcoma: a review and update
Identifieur interne : 003A97 ( Main/Exploration ); précédent : 003A96; suivant : 003A98Oral Kaposi's sarcoma: a review and update
Auteurs : Mahnaz Fatahzadeh [États-Unis] ; Robert A. Schwartz [États-Unis]Source :
- International Journal of Dermatology [ 0011-9059 ] ; 2013-06.
Abstract
Kaposi's sarcoma (KS) is an important mucocutaneous neoplasm with four well‐known clinicopathologic types. Involvement of the oral cavity may be seen in all variants but is most common with AIDS‐KS. The latter may signal undiagnosed HIV infection. Its common association with disseminated disease has potentially important diagnostic and therapeutic implications. Oral KS (OKS) most often affects the hard and soft palate, gingiva, and dorsal tongue with plaques or tumors of coloration ranging from non‐pigmented to brownish‐red or violaceous. Its involvement ranges from an incidental finding to proliferative tumor formation that interferes with mastication. OKS needs to be distinguished clinically from other entities, including pyogenic granuloma, hemangioma, bacillary angiomatosis, and gingival enlargement caused by cyclosporine, a drug frequently used in recipients of organ transplantation. KS may flare as part of the immune reconstitution inflammatory syndrome in HIV patients or develop in the context of iatrogenic immunosuppression. Management, which may depend upon a variety of factors including the clinicopathologic type of KS and results of staging, ranges from no treatment to local measures such as intralesional vinblastine or systemic administration of cytotoxic chemotherapy for disseminated disease. Modification of immunosuppressive regimens often helps control post‐transplant OKS but enhances the risk of graft rejection. Screening donors and recipients of organ transplants for HHV‐8, with prophylactic treatment if infected as well as institution of sirolimus early after transplantation, are proposed strategies aimed at preventing post‐transplant OKS.
Url:
DOI: 10.1111/j.1365-4632.2012.05758.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 006B93
- to stream Istex, to step Curation: 006B93
- to stream Istex, to step Checkpoint: 000125
- to stream Main, to step Merge: 003B06
- to stream Main, to step Curation: 003A97
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Oral Kaposi's sarcoma: a review and update</title><author><name sortKey="Fatahzadeh, Mahnaz" sort="Fatahzadeh, Mahnaz" uniqKey="Fatahzadeh M" first="Mahnaz" last="Fatahzadeh">Mahnaz Fatahzadeh</name></author><author><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E5C9A6A162C267E19069C7F79B67AE9D96EFC3EA</idno><date when="2013" year="2013">2013</date><idno type="doi">10.1111/j.1365-4632.2012.05758.x</idno><idno type="url">https://api.istex.fr/document/E5C9A6A162C267E19069C7F79B67AE9D96EFC3EA/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">006B93</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">006B93</idno><idno type="wicri:Area/Istex/Curation">006B93</idno><idno type="wicri:Area/Istex/Checkpoint">000125</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000125</idno><idno type="wicri:doubleKey">0011-9059:2013:Fatahzadeh M:oral:kaposi:s</idno><idno type="wicri:Area/Main/Merge">003B06</idno><idno type="wicri:Area/Main/Curation">003A97</idno><idno type="wicri:Area/Main/Exploration">003A97</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Oral Kaposi's sarcoma: a review and update</title><author><name sortKey="Fatahzadeh, Mahnaz" sort="Fatahzadeh, Mahnaz" uniqKey="Fatahzadeh M" first="Mahnaz" last="Fatahzadeh">Mahnaz Fatahzadeh</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Oral Medicine, New Jersey Dental School, NJ, Newark</wicri:regionArea><wicri:noRegion>Newark</wicri:noRegion></affiliation><affiliation></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author><author><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name><affiliation wicri:level="1"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dermatology and Pathology, New Jersey Medical School, NJ, Newark</wicri:regionArea><wicri:noRegion>Newark</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">International Journal of Dermatology</title><title level="j" type="alt">INTERNATIONAL JOURNAL OF DERMATOLOGY</title><idno type="ISSN">0011-9059</idno><idno type="eISSN">1365-4632</idno><imprint><biblScope unit="vol">52</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="666">666</biblScope><biblScope unit="page" to="672">672</biblScope><biblScope unit="page-count">7</biblScope><date type="published" when="2013-06">2013-06</date></imprint><idno type="ISSN">0011-9059</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0011-9059</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Kaposi's sarcoma (KS) is an important mucocutaneous neoplasm with four well‐known clinicopathologic types. Involvement of the oral cavity may be seen in all variants but is most common with AIDS‐KS. The latter may signal undiagnosed HIV infection. Its common association with disseminated disease has potentially important diagnostic and therapeutic implications. Oral KS (OKS) most often affects the hard and soft palate, gingiva, and dorsal tongue with plaques or tumors of coloration ranging from non‐pigmented to brownish‐red or violaceous. Its involvement ranges from an incidental finding to proliferative tumor formation that interferes with mastication. OKS needs to be distinguished clinically from other entities, including pyogenic granuloma, hemangioma, bacillary angiomatosis, and gingival enlargement caused by cyclosporine, a drug frequently used in recipients of organ transplantation. KS may flare as part of the immune reconstitution inflammatory syndrome in HIV patients or develop in the context of iatrogenic immunosuppression. Management, which may depend upon a variety of factors including the clinicopathologic type of KS and results of staging, ranges from no treatment to local measures such as intralesional vinblastine or systemic administration of cytotoxic chemotherapy for disseminated disease. Modification of immunosuppressive regimens often helps control post‐transplant OKS but enhances the risk of graft rejection. Screening donors and recipients of organ transplants for HHV‐8, with prophylactic treatment if infected as well as institution of sirolimus early after transplantation, are proposed strategies aimed at preventing post‐transplant OKS.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><country name="États-Unis"><noRegion><name sortKey="Fatahzadeh, Mahnaz" sort="Fatahzadeh, Mahnaz" uniqKey="Fatahzadeh M" first="Mahnaz" last="Fatahzadeh">Mahnaz Fatahzadeh</name></noRegion><name sortKey="Fatahzadeh, Mahnaz" sort="Fatahzadeh, Mahnaz" uniqKey="Fatahzadeh M" first="Mahnaz" last="Fatahzadeh">Mahnaz Fatahzadeh</name><name sortKey="Schwartz, Robert A" sort="Schwartz, Robert A" uniqKey="Schwartz R" first="Robert A." last="Schwartz">Robert A. Schwartz</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003A97 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003A97 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:E5C9A6A162C267E19069C7F79B67AE9D96EFC3EA
|texte= Oral Kaposi's sarcoma: a review and update
}}
| This area was generated with Dilib version V0.6.31. |  |